NFL odds Week 4: Lines for every game

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A showdown between Super Bowl and NFL MVP-winning quarterbacks, a key AFC contest and a reunion of bitter rivals highlight the Week 4 schedule.

Kansas City’s Patrick Mahomes will play Tampa Bay’s Tom Brady on Sunday Night Football, Buffalo and Baltimore will hold a battle of 2-1 AFC teams with Super Bowl aspirations and the Commanders and Cowboys will resume their longtime rivalry.

Here’s everything you need to know about the NFL odds for Week 4 — the point spreads, moneylines and total over/unders (with all NFL odds via FOX Bet).

All times ET

THURSDAY’S GAME

Dolphins @ Bengals (8:15 p.m. ET Thursday, Amazon Prime)

Point spread: Bengals -3.5 (Bengals favored to win by more than 3.5 points, otherwise Dolphins cover)
Moneyline: Bengals -213 favorites to win (bet $10 to win $14.69 total); Dolphins +160 underdogs to win (bet $10 to win $26 total)
Total scoring over/under: 46.5 points scored by both teams combined

Miami Dolphins

MIA

Cincinnati Bengals

CIN

RELATED: How to Bet Dolphins-Bengals

SUNDAY’S GAMES

Vikings @ Saints in London (9:30. a.m. ET Sunday, NFL Network)

Point spread: Vikings -3 (Vikings favored to win by more than 3 points, otherwise Saints cover)
Moneyline: Vikings -167 favorites to win (bet $10 to win $15.99 total); Saints +130 underdogs to win (bet $10 to win $23 total)
Total scoring over/under: 43.5 points scored by both teams combined

Minnesota Vikings

MIN

New Orleans Saints

NO

RELATED: How to Bet Vikings-Saints

Browns @ Falcons (1 p.m.ET Sunday, CBS)

Point spread: Browns -1.5 (Browns favored to win by more than 1.5 points, otherwise Falcons cover)
Moneyline: Browns -125 favorites to win (bet $10 to win $18 total); Falcons +100 underdogs to win (bet $10 to win $20 total)
Total scoring over/under: 49.5 points scored by both teams combined

Cleveland Browns

CLE

Atlanta Falcons

ATL

RELATED: How to Bet Browns-Falcons

Commanders @ Cowboys (1 p.m. ET Sunday, FOX)

Point spread: Cowboys -3.5 (Cowboys favored to win by more than 3.5 points, otherwise Commanders cover)
Moneyline: Cowboys -175 favorites to win (bet $10 to win $15.71 total); Commanders +135 underdogs to win (bet $10 to win $23.50 total)
Total scoring over/under: 41.5 points scored by both teams combined

Washington Commanders

WAS

Dallas Cowboys

DAL

RELATED: How to Bet Commanders-Cowboys

Seahawks @ Lions (1 p.m. ET Sunday, FOX)

Point spread: Lions -4.5 (Lions favored to win by more than 4.5 points, otherwise Seahawks cover)
Moneyline: Lions -213 favorites to win (bet $10 to win $14.69 total); Seahawks +160 underdogs to win (bet $10 to win $26 total)
Total scoring over/under: 48.5 points scored by both teams combined

Seattle Seahawks

SEA

Detroit Lions

DET

RELATED: How to Bet Seahawks-Lions

Titans @ Colts (1 p.m. ET Sunday, FOX)

Point spread: Colts -3.5 (Colts favored to win by more than 3.5 points, otherwise Titans cover)
Moneyline: Colts -182 favorites to win (bet $10 to win $15.49 total); Titans +140 underdogs to win (bet $10 to win $24 total)
Total scoring over/under: 42.5 points scored by both teams combined

Tennessee Titans

TEN

Indianapolis Colts

IND

RELATED: How to Bet Titans-Colts

Bears @ Giants (1 p.m. ET Sunday, FOX)

Point spread: Giants -3 (Giants favored to win by more than 3 points, otherwise Bears cover)
Moneyline: Giants -175 favorites to win (bet $10 to win $15.71 total); Bears +135 underdogs to win (bet $10 to win $23.50 total)
Total scoring over/under: 39 points scored by both teams combined

Chicago Bears

CHI

New York Giants

NYG

RELATED: How to Bet Bears-Giants

Jaguars @ Eagles (1 p.m. ET Sunday, CBS)

Point spread: Eagles -6.5 (Eagles favored to win by more than 6.5 points, otherwise Jaguars cover)
Moneyline: Eagles -278 favorites to win (bet $10 to win $13.60 total); Jaguars +205 underdogs to win (bet $10 to win $30.50 total)
Total scoring over/under: 46.5 points scored by both teams combined

Jacksonville Jaguars

JAX

Philadelphia Eagles

PHI

RELATED: How to Bet Jaguars-Eagles

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Jets @ Steelers (1 p.m. ET Sunday, CBS)

Point spread: Steelers -3 (Steelers favored to win by more than 3 points, otherwise Jets cover)
Moneyline: Steelers -167 favorites to win (bet $10 to win $15.99 total); Jets +130 underdogs to win (bet $10 to win $23 total)
Total scoring over/under: 41.5 points scored by both teams combined

New York Jets

NYJ

Pittsburgh Steelers

PIT

RELATED: How to Bet Jets-Steelers

Bills @ Ravens (1 p.m. ET Sunday, CBS)

Point spread: Bills -3 (Bills favored to win by more than 3 points, otherwise Ravens cover)
Moneyline: Bills -167 favorites to win (bet $10 to win $15.99 total); Ravens +130 underdogs to win (bet $10 to win $23 total)
Total scoring over/under: 51.5 points scored by both teams combined

Buffalo Bills

BUF

Baltimore Ravens

BAL

RELATED: How to Bet Bills-Ravens

Chargers @ Texans  (1 p.m. ET Sunday, CBS)

Point spread: Chargers -5.5 (Chargers favored to win by more than 5.5 points, otherwise Texans cover)
Moneyline: Chargers -227 favorites to win (bet $10 to win $14.41 total); Texans +175 underdogs to win (bet $10 to win $27.50 total)
Total scoring over/under: 44.5 points scored by both teams combined

Los Angeles Chargers

LAC

Houston Texans

HOU

RELATED: How to Bet Chargers-Texans

Cardinals @ Panthers (4:05 p.m. ET Sunday, FOX)

Point spread: Panthers -1.5 (Panthers favored to win by more than 1.5 points, otherwise Cardinals cover)
Moneyline: Panthers -120 favorites to win (bet $10 to win $18.33 total); Cardinals -105 underdogs to win (bet $10 to win $19.52 total)
Total scoring over/under: 42.5 points scored by both teams combined

Arizona Cardinals

ARI

Carolina Panthers

CAR

RELATED: How to Bet Cardinals-Panthers

Patriots @ Packers (4:25 p.m. ET Sunday, CBS)

Point spread: Packers -10 (Packers favored to win by more than 10 points, otherwise Patriots cover)
Moneyline: Packers -500 favorites to win (bet $10 to win $12 total); Patriots +300 underdogs to win (bet $10 to win $40 total)
Total scoring over/under: 40.5 points scored by both teams combined

New England Patriots

NE

Green Bay Packers

GB

RELATED: How to Bet Patriots-Packers

Broncos @ Raiders (4:25 p.m. ET Sunday, CBS)

Point spread: Raiders -2.5 (Raiders favored to win by more than 2.5 points, otherwise Broncos cover)
Moneyline: Raiders -149 favorites to win (bet $10 to win $16.71 total); Broncos +115 underdogs to win (bet $10 to win $21.50 total)
Total scoring over/under: 45.5 points scored by both teams combined

Denver Broncos

DEN

Las Vegas Raiders

LV

RELATED: How to Bet Broncos-Raiders

Chiefs @ Buccaneers (8:20 p.m. ET Sunday, NBC)

Point spread: Chiefs -1.5 (Chiefs favored to win by more than 1.5 points, otherwise Buccaneers cover)
Moneyline: Chiefs -120 favorites to win (bet $10 to win $18.33 total); Buccaneers -105 underdogs to win (bet $10 to win $19.52 total)
Total scoring over/under: No line available

Kansas City Chiefs

KC

Tampa Bay Buccaneers

TB

RELATED: How to Bet Chiefs-Buccaneers

MONDAY’S GAME

Rams @ 49ers (8:15 p.m. ET Monday, ESPN)

Point spread: 49ers -1.5 (49ers favored to win by more than 1.5 points, otherwise Rams cover)
Moneyline: 49ers -120 favorites to win (bet $10 to win $18.33 total); Rams -105 underdogs to win (bet $10 to win $19.52 total)
Total scoring over/under: 42.5 points scored by both teams combined

Los Angeles Rams

LAR

San Francisco 49ers

SF

RELATED: How to Bet Rams-49ers

Our experts have you covered on everything you need for this weekend from a betting perspective:

Warren Sharp’s Betting Edges

Geoff’s Best NFL Bets

Pat Everson’s Sharp Bets

Jason McIntyre’s Best NFL Bets

Sammy’s Best Bets 

Geoff’s Best Bets for College Football Week 5

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